Hormone | Stimuli for Release | Mechanism of Synthesis/Release | Target Tissue(s) | Effects and MOA | Feedback Regulation |
ACTH | Corticotrophs (CRH) | Exocytosis; increase cAMP, which activates PKA | Adrenal Gland | Stimulates production of glucocorticoids and rogens by adrenal cortex | Negative |
TSH | Thyrotrophs (TRH) | Exocytosis; activates PLC, which releases IP3/DAG and increase intracellular Ca2+ | Thyroid Gland | Stimulates production of thyroid hormones, T3 & T4, by thyroid follicular cells | Negative |
GH | Somatotrophs (GHRH) | Exocytosis; synthesized in rough ER | Liver, adipose tissue | Stimulates postnatal body growth; stimulates triglyceride lipolysis | Negative |
FSH | Gonadotrophs (GnRH) | Exocytosis; synthesized in the rough ER | Ovaries, testes | Growth of reproductive system; regulates spermatogenesis | Negative |
LH | Gonadotrophs (GnRH) | Exocytosis; synthesized in the rough ER | Ovaries, testes | Sex hormone production | Negative |
PRL | Lactotrophs (aka Mammotrophs) | Exocytosis; synthesized in the rough ER | Ovaries, mammary glands | Secretion of estrogens/progesterone; mild production | Positive |
Antidiuretic hormone (ADH) Or Arginine vasopressin (AVP) | Rise in the osmolarity of the blood and a decrease in blood volume | Exocytosis; synthesis in rough ER | Kidneys or arterioles | Stimulates water retention; raises blood pressure by contracting arteries | Negative |
Oxytocin | Breast-feeding stimulates sensory nerves and neural input from the female reproductive tract during childbirth | Exocytosis; synthesis in rough ER | Uterus, mammary glands | Uterine contractions & lactation; | Positive |
T4 (thyroxine) & T3 (triiodothronine) | TSH | Exocytosis; synthesized in the rough ER | All tissues, | Increases basal metabolic rate | Negative |
Cortisol (glucocorticoid) | ACTH | Made from cholesterol and released directly into the blood; zona fasciculata | All Tissues | Increase plasma glucose; increase gluconeogenesis; increased fat breakdown; block osteoblast and Ca2+ absorption | Negative |
Aldosterone (mineral corticoids) | Angiotensin II | Made from cholesterol and released directly into the blood; zona gomerulosa | Kidneys | Increases sodium reaborption and passive water reabsorption in the collecting ducts of the kidenys | Negative |
Androgens (sex steroids) | ACTH | Made from cholesterol and released directly into the blood; zona reticularis | Testes, penis | Male reproductive... | |
Cotton gin
More Area & Country Studies Essays
essays:
Alfarería Nativa Americana
Alfarería Nativa Americana Mientras la mayor parte del tiempo les refiere a las tribus nómadas en los Estados Unidos, el término 'Nativo americano' medios alguien que está nativo a las Américas. Aztecas, mayas, Incas y varios otro no-North se han referido tribus americanas a, por muchas fuentes, ...
New York the Empire state
NEW YORK - THE EMPIRE STATE New York is in the northeastern United States. It is one of the middle atlantic states. The Dutch built its first settlements. Then,England ruled New York for more than a hundred years. In 1788,New York became one of the orignal 13 states. First I am going to tell you ...
Egypt
EGYPT The majority of people have various ways of viewing cultures. Because of close-mindedness and lack of cultural education, people have a difficult time interacting with different societies. I feel that people shouldn't stereotype because this might lead to misjudgment. For example, I have ...
Sweden
Sweden Today, Sweden is a striving country using the most of the resources it has. It's located in Northern Europe and is considered large in comparison to the surrounding nations. In fact it has a larger mass then California. Within these 449,964 square kilometers lies running water in tremendous ...
Australia and the Great Barrier Reef
An essay about the great barrier reef in Australia - The Great Barrier Reef The Great Barrier Reef is the biggest group of coral reefs in the world. It stretches along the coast on the north-east part of Australia. It is called the Great Barrier Reef because it creates a barrier between the ...